Result for 6A81A4260F941602B0C60D5FAAA288520F804134

Query result

Key Value
FileName./usr/lib64/R/library/Rsolid/Meta/links.rds
FileSize101
MD5A31A60A4D2A304C45C1DB977A6A82102
SHA-16A81A4260F941602B0C60D5FAAA288520F804134
SHA-2564AE44F9331A85EC17442F45128AD26C95215D7E5BD5551635755257831C12BC2
SSDEEP3:FttVFHktVFlYP7qJ2xvPiJcpOIGzjpERln:XtVFEnFU7FiJcIkn
TLSHT19AB012EC09206030CE142233524D8F3C0E478002EA2044E6E022110542B00A784C223A
hashlookup:parent-total2
hashlookup:trust60

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Parents (Total: 2)

The searched file hash is included in 2 parent files which include package known and seen by metalookup. A sample is included below:

Key Value
MD528246D1E5217185AD82EC8E90DD1A85A
PackageArchaarch64
PackageDescription Rsolid is an R package for normalizing fluorescent intensity data from ABI/SOLiD second generation sequencing platform. It has been observed that the color-calls provided by factory software contain technical artifacts, where the proportions of colors called are extremely variable across sequencing cycles. Under the random DNA fragmentation assumption, these proportions should be equal across sequencing cycles and proportional to the dinucleotide frequencies of the sample. Rsolid implements a version of the quantile normalization algorithm that transforms the intensity values before calling colors. Results show that after normalization, the total number of mappable reads increases by around 5%, and number of perfectly mapped reads increases by 10%. Moreover a 2-5% reduction in overall error rates is observed, with a 2-6% reduction in the rate of valid adjacent color mis-matches. The latter is important, since it leads to a decrease in false-positive SNP calls. The normalization algorithm is computationally efficient. In a test we are able to process 300 million reads in 2 hours using 10 computer cluster nodes. The engine functions of the package are written in C for better performance.
PackageMaintainerFedora Project
PackageNameR-Rsolid
PackageRelease18.fc24
PackageVersion0.9.31
SHA-12C89EBC2F978BD797D6125B6FCDD950009D68501
SHA-25685ECC7ACDAD09BC431262D66615350F1C0BA127650A944674337A1C050852636
Key Value
MD58D3B1680151960E899C465997B4ACB46
PackageArchppc64
PackageDescription Rsolid is an R package for normalizing fluorescent intensity data from ABI/SOLiD second generation sequencing platform. It has been observed that the color-calls provided by factory software contain technical artifacts, where the proportions of colors called are extremely variable across sequencing cycles. Under the random DNA fragmentation assumption, these proportions should be equal across sequencing cycles and proportional to the dinucleotide frequencies of the sample. Rsolid implements a version of the quantile normalization algorithm that transforms the intensity values before calling colors. Results show that after normalization, the total number of mappable reads increases by around 5%, and number of perfectly mapped reads increases by 10%. Moreover a 2-5% reduction in overall error rates is observed, with a 2-6% reduction in the rate of valid adjacent color mis-matches. The latter is important, since it leads to a decrease in false-positive SNP calls. The normalization algorithm is computationally efficient. In a test we are able to process 300 million reads in 2 hours using 10 computer cluster nodes. The engine functions of the package are written in C for better performance.
PackageMaintainerFedora Project
PackageNameR-Rsolid
PackageRelease18.fc24
PackageVersion0.9.31
SHA-14070964DA9E48A22076483339A7C41CD203E1C2F
SHA-25617131E889818CDC14FE5E8F7B63CF1ACAB2EAC92E28889AC6442DBC185CD4CD9