Result for 7C1A1B61448820B47542A6A00A7518D50DFD7999

Query result

Key Value
FileName./usr/bin/toppic
FileSize4092736
MD55BE4FD810FF419A09707B0CBBA776794
SHA-17C1A1B61448820B47542A6A00A7518D50DFD7999
SHA-2569CF26621BFBE59ADBCBB958253788CE5370B81AC864FD0446AACF97EC20A0367
SSDEEP24576:YT0TbVeHGt2a+1iY4Ebr0MIcH/2JCw9gYd5CkwTV2Wog1afegvqUTxVc:YoTbr2+4BOgwiWuTWgAfegb
TLSHT1E2161A557FC45F6BC8EC8FB9DC3AC276006D2D83B0464E2A7CD11A8D9B276CE0B42959
hashlookup:parent-total1
hashlookup:trust55

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Parents (Total: 1)

The searched file hash is included in 1 parent files which include package known and seen by metalookup. A sample is included below:

Key Value
FileSize1924552
MD5DDBD9BD63D2973883CDC5A8EC720E092
PackageDescriptionTop-down proteoform identification and characterization (programs) The TopPIC Suite consists of four software tools for the interpretation of top-down mass spectrometry data: TopFD, TopPIC, TopMG, and TopDiff. . -TopFD (Top-down mass spectral Feature Detection) is a software tool for top-down spectral deconvolution and a successor to MS-Deconv. It groups top-down spectral peaks into isotopomer envelopes and converts isotopomer envelopes to monoisotopic neutral masses. In addition, it extracts proteoform features from LC-MS or CE-MS data. . -TopPIC (Top-down mass spectrometry based Proteoform Identification and Characterization) identifies and characterizes proteoforms at the proteome level by searching top-down tandem mass spectra against a protein sequence database. TopPIC is a successor to MS-Align+. It efficiently identifies proteoforms with unexpected alterations, such as mutations and post-translational modifications (PTMs), accurately estimates the statistical significance of identifications, and characterizes reported proteoforms with unknown mass shifts. It uses several techniques, such as indexes, spectral alignment, generation function methods, and the modification identification score (MIScore), to increase the speed, sensitivity, and accuracy. . -TopMG (Top-down mass spectrometry based proteoform identification using Mass Graphs) is a software tool for identifying ultra-modified proteoforms by searching top-down tandem mass spectra against a protein sequence database. It is capable of identifying proteoforms with multiple variable PTMs and unexpected alterations, such as histone proteoforms and phosphorylated ones. It uses mass graphs, which efficiently represent candidate proteoforms with multiple variable PTMs, to increase the speed and sensitivity in proteoform identification. In addition, approximate spectrum-based filtering methods are employed for protein sequence filtering, and a Markov chain Monte Carlo method (TopMCMC) is used for estimating the statistical significance of identifications. . -TopDiff (Top-down mass spectrometry-based identification of Differentially expressed proteoforms) compares the abundances of proteoforms and finds differentially expressed proteoforms by using identifications of top-down mass spectrometry data of several protein samples.
PackageMaintainerThe Debichem Group <debichem-devel@lists.alioth.debian.org>
PackageNametoppic
PackageSectionscience
PackageVersion1.3.0+dfsg1-4+b1
SHA-1D87ED7AE4A34008599E7F1E2AB90DB330FAD71FD
SHA-256ED7944878C55384A39A37C282A2008C66976F99EC3B75DE8E3A7D138FA3957B9